Get caught up quickly on the top news and calls moving stocks with these Top Fives, as compiled by the editors of The Fly. 

1. STOCK NEWS: 

• Merck (MRK) rises after its oral anti-viral molnupiravir was shown to lower the risk of hospitalization and death by about 50% in a non-hospitalized COVID-19 population with mild-to-moderate disease [more]
• Five9 (FIVN) and Zoom Video (ZM) shares both rose after Five9 shareholders voted to reject a proposed takeover and the deal with Zoom was called off [more]
• General Motors (GM) reported Q3 U.S. sales of 446,997 vehicles, down over 200,000 units from last year due to "semiconductor supply chain disruptions and historically low inventories" [more]
• Electronic Arts (EA) announced the appointment of Laura Miele as the company's COO and that Blake Jorgensen, EA's COO and CFO, will begin a process to exit [more]
• Coty (COTY) to sell partial stake in Wella to KKR (KKR) [more]

2. WALL STREET CALLS: 

• IBM (IBM) initiated with a Buy at Jefferies [more]
• Alibaba (BABA) downgraded to Outperform from Strong Buy at Raymond James [more]
• Susquehanna cuts MGM Resorts (MGM) to Negative on digital prospects hit from DraftKings (DKNG) bid for Entain (GMVHF) [more]
• Netflix (NFLX) price target raised to $685 from $600 at Guggenheim [more]
• Dollar Tree (DLTR) downgraded to Sector Weight from Overweight at KeyBanc [more]

3. AROUND THE WEB: 

• Guardant Health (GH) considering possible takeover of NeoGenomics (NEO), Bloomberg says [more]
• Google (GOOGL) scraps plans to offer bank accounts to users, WSJ reports [more]
• Disney (DIS) settles "Black Widow" contract suit with Scarlett Johansson, WSJ reports [more]
• Thousands of Coinbase (COIN) customers impacted by hack, BleepingComputer reports [more]
• White House pressing airlines on mandating employee vaccination, Reuters says [more]

4. MOVERS: 

• Moderna (MRNA), Pfizer (PFE), Adagio Therapeutics (ADGI) and AbCellera Biologics (ABCL) were among stocks that slid after Merck's report of its COVID pill data [more]
• The Metals Company (TMC) up after a regulatory filing showed CEO Gerard Barron bought 34K shares and director Andrei Karkar bought 2.25M shares of the company’s stock [more]
• Volta (VLTA) higher after Roth Capital initiated coverage of the stock with a Buy rating and $18 price target [more]
• Omeros (OMER) lower after announcing the FDA notified it of deficiencies in the company's Biologics License Application for narsoplimab [more]
• Canopy Growth (CGC) falls after BofA downgraded the stock to Neutral from Buy [more]

5. EARNINGS/GUIDANCE: 

• QuickLogic (QUIK) raises Q3 revenue view [more]
• Guidewire (GWRE) backs FY22 revenue view of $785M at midpoint at analyst day [more]
• Allegion (ALLE) lowers FY21 adjusted EPS view [more]
• Jefferies Financial (JEF) reported Q3 results [more]
• Applied Materials (AMAT) said its guidance for the fourth quarter of fiscal 2021 is unchanged after announcing its CFO is departing the company [more]

INDEXES: 

The Dow closed higher by 482.54, or 1.43%, to 34,326.46, the Nasdaq was up 118.12, or 0.82%, to 14,566.70, and the S&P 500 rose 49.50, or 1.15%, to 4,357.04.